Florida's New Emergency 7-OH Rule: What Customers and Distributors Should Know

Florida has introduced significant new restrictions on 7-hydroxymitragynine (7-OH). The following summary explains what changed, which compounds are covered, and what it means for those following the regulatory landscape in the state. It is intended as general information and does not constitute legal advice.

 

What Happened

On June 22, 2026, the Florida Attorney General signed an emergency rule expanding the state's Schedule I controlled-substance list to include concentrated 7-OH and several chemically related compounds. State officials described the action as a response to highly concentrated and chemically altered products, citing public-safety concerns. Because it was filed as an emergency measure, the rule took effect immediately rather than proceeding through the standard rulemaking period.

 

What the Rule Restricts

The rule introduces two principal requirements. First, it establishes a strict concentration cap: covered compounds may not exceed approximately 1 milligram per gram in solid or pill products, or 1 milligram per milliliter in liquids. Second, it imposes a ratio requirement: any product containing these compounds must also contain at least 100 times more naturally occurring mitragynine by mass. Together, these provisions target isolated, highly concentrated, or semi-synthetic formulations rather than minimally processed botanical material.

 

Which Compounds Are Covered

In addition to 7-OH itself, the rule names several related compounds, including mitragynine pseudoindoxyl, 7-acetoxymitragynine, 9-hydroxycorynantheidine, 10-hydroxycorynantheidine, MGM-15, and MGM-16. Naming these compounds explicitly is intended to address chemically modified analogs that might otherwise fall outside an existing definition.

 

What It Means for Customers and Distributors

  • For Customers: The rule changes which products are legally available within Florida. Products outside the permitted thresholds are now treated as controlled substances in the state.

  • For Distributors: The rule affects what may be sold, stored, or moved into and through Florida, with significant penalties for non-compliant products.

 

Staying Informed and Compliant

Regulations in this area are evolving quickly and vary considerably from state to state. The rule has also already been subject to legal challenge, so its details may continue to develop. We encourage all readers to rely on primary sources and official notices, to follow guidance from the Florida Attorney General's office, and to consult a qualified attorney for advice specific to their circumstances.